Кафедра біомедичної інженерії (БМІ)
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Публікація 3D modeling, errors sources, internal map, optical detection, surgical navigation system(American Scientific Publishers, 2015) Аврунін, О. Г.; Alkhorayef, M.; Saied, H. F. I.; Tymkovych, M.Several causes of spatial errors in surgical navigation system have been investigated for several systems. These include identification error of the external features used for registration, geometrical distortion in the preoperative images, and tracking error of the surgical instruments. Another potentially important source of error is the patient head position detection retrospectively and concurrent with surgery. The visualization of target zone is carried out according to reference landmark points inside the center of the brain as well as an automatic algorithm for contour recognition (based on 3D segmentation and computer morphometry) was applied to edge the contour. Moreover, the optical navigation system was used to assess the accuracy of determination the position of the surgical instrument inside patient head construction using the "internal map" describing the anatomy of the brain. The major sources of errors occurring in the unit of position detection of the optical navigation system were considered. Furthermore, parts of the errors that could appear were simulated while operating the surgical navigation system. Eventually the research included the possibility of using different filters depending on natural source of noise that was also simulated and analyzed.Публікація 3D-bioprinting system for fabrication of alginate microfibers(АНПРЭ, ХНУРЭ, Издательство «Точка», 2017) Avakian, A.The given work is devoted to the theme of 3D-printing of alginate microfibers with encapsulated stem cells which are used for the nerve regeneration. The motorized printing device is developed and tested. The appropriate software controls the device and allows to design the printing structures.Публікація 3D-reconstruction of anatomical structures using rapid prototyping for medical applications(КрНУ імені Михайла Остроградського, 2016) Аврунін, О. Г.; Avrunin, O. G.; Tymkovych, M.; Filzov, M.3D-reconstruction of anatomical structures using rapid prototyping for medical applications is described.Публікація 3D-биопринтинг воздухоносных путей(ХНУРЕ, 2016) Наконечный, И. М.This work is devoted to the use of 3D-Bioprinting in the field of biomedical engineering, namely the airways bioprinting. Damage to the trachea - a common phenomenon. Known methods of treatments worse than 3D-Bioprinting. To create researchers have resorted to the tracheal tissue engineering. This science is similar to programming code but instead it creates objects from body cells, including, from muscle and cartilage. Just narrowing airways surgically placed into the trachea insert manufactured using 3D-Bioprinting. 3D-Bioprinting is directly relevant to improving and saving lives, as well as the ability to completely transform many of the risky surgical procedures. Работа посвящена использованию 3D-биопечати в биомедицинской инженерии, а именно биопечати дыхательных путей. Повреждение трахеи - частое явление. Известные методы лечения хуже, чем 3D-биопечать. Исследователи прибегли к инженерии ткани трахеи. Эта похоже на программный код, когда создаются объекты из клеток тела, в том числе из мышц и хрящей. 3D-биопечать имеет прямое отношение к улучшению и спасение жизней, а также способна полностью изменить многие рискованные хирургические процедуры.Публікація 3D-реконструкция структур легких по данным компьютерной томографии для контроля качества рентгенограмм(КрНУ, 2018) Роговец, В. Е.; Тымкович, М. Ю.; Аверьянова, Л. А.Приводятся результаты исследования возможностей 3Д реконструкции структур легких по данным КТ для контроля качества рентгенограмм. Предлагается технология изготовления морфологического рентгенэквивалентного фантома легких.Публікація 3D-технологии при совершенствовании научно-педагогического процесса в оториноларингологии(НМУ им. Богомольца, 2016) Журавлев, А. С.; Аврунін, О. Г.; Калашник, Ю. М.; Фильтзов, М.Рассматриваются 3D-технологии при совершенствовании научно-педагогического процесса в оториноларингологииПублікація A comprehensive study of molecular hybridization techniques in cytogenetics with a focus on chronic myeloid leukaemia(ВНТУ, 2024) Molodetska, D.Early and accurate diagnosis of chromosomal abnormalities is crucial for preventing congenital disorders. However, cytogenetics faces limitations in Ukraine, likely due to a lack of specialists and public awareness. This study aims to investigate these limitations and explore strategies to promote cytogenetics in Ukraine. By increasing access and awareness, more people can benefit from this potentially life-saving field.Публікація A Method for Prognosis of Primary Open-Angle Glaucoma(International Review on Computers and Software., 2013) Vysotskaja, E.; Strashnenko, A.; Prasol, I.A method for prognosis of primary open-angle glaucoma (POAG) using the mathematical apparatus of Markov processes is developed in the article. The mathematical apparatus of Markov processes with discrete states and discrete time was used to describe the course of glaucoma. According to the clinical approbation of the proposed method, the prognosis was made unmistakably in 16 surveyed patients. Prognosis was confirmed in 82% of cases. The proposed method increases the prognosis of POAG development significantly. The introduction of this method for POAG prognosis in ophthalmology practice allows improving the quality level of medical service for patients.Публікація A Method of Computer Testing of the Level of Development of Graphic Skills(2014) Аврунін, О. Г.; Selivanova, K.; Saied, H. F. I.This paper describes a computer-aided method of testing fine motor skills of the dominant hand and introduces a technique for estimating the level of development of the fine motor skills (using graphical tablet). The paper provides a set of basic parameters that serves as criteria for performance evaluation methodology. The analysis of the tests results is carried out with a computer program that allows determining the level of development of motor skills based on quantitative assessments.Публікація A single-electrode electrochemical system for multiplex electrochemiluminescence analysis based on a resistance induced potential difference†(Chemical Science, 2018) Gao, W.; Muzyka, K.; Ma, X.; Loua, B.; Xu, G.Developing low-cost and simple electrochemical systems is becoming increasingly important but still challenged for multiplex experiments. Here we report a single-electrode electrochemical system (SEES) using only one electrode not only for a single experiment but also for multiplex experiments based on a resistance induced potential difference. SEESs for a single experiment and multiplex experiments are fabricated by attaching a self-adhesive label with a hole and multiple holes onto an ITO electrode, respectively. This enables multiplex electrochemiluminescence analysis with high sensitivity at a very low safe voltage using a smartphone as a detector. For the multiplex analysis, the SEES using a single electrode is much simpler, cheaper and more user-friendly than conventional electrochemical systems and bipolar electrochemical systems using electrode arrays. Moreover, SEESs are free from the electrochemiluminescent background problem from driving electrodes in bipolar electrochemical systems. Since numerous electrodes and cover materials can be used to fabricate SEESs readily and electrochemistry is being extensively used, SEESs are very promising for broad applications, such as drug screening and high throughput analysis.Публікація Acoustic excitation of electric field in water solution NaCl(Poland, Warszawa, 2019) Аврунін, О. Г.; Bondarenko, I. S.; Bondarenko, S. I.; Kuzmenko, Y. V.; Pinaieva, O. Yu.; Kisała, P.; Tleshova, A.; Luganskaya, S.Acoustic excitation of electric field in water solution NaCl is described.Публікація Acoustomagnetic detection of magnetic nanoparticles in a model(The International Journal of Artificial Organs, 2019) Bondarenko, I. S.; Аврунін, О. Г.; Gryshkov, O.; Glasmacher, B.; Bondarenko, S. I.; Krevsun, A. V.; Rakhimova, M. V.Magnetic nanoparticles (MNPs) are used in medicine for targeted drug delivyry to the area of the cancer. The installation consists of the ultrasound generator, the permanent magnet, the glass containerwith the colloidal mixture, the multi-turn coil about of the glass tube and the voltmeter. The experimental result corrilates with the calculated ones. It is suggested that AMM can used to detect MNPs in the real biological substance.Публікація Acoustomagnetic Registration of Magnetic Nanoparticles in a Liquid Medium(Begell House, Inc, 2019) Аврунін, О. Г.; Avrunin, O. G.; Bondarenko, I. S.; Rakhimova, M. V.; Bondarenko, S. I.; Krevsun, A. V.; Kulish, S. M.The technique and results of experiments on the registration of magnetic nanoparticles in a colloidal solution using the combined effect of ultrasound and a direct magnetic field are presented. The possibility of using this technique to control the content of magnetic nanoparticles in a biological substance is discussed.Публікація Actual problems of stroke disease cure in Egypt(Харків, ХНУРЕ, 2019) Bayoumy, Hassan; Averyanova, L. O.The causes of stroke disease in Egypt are considered. The diagnosis of stroke is explained, and the used diagnostic instruments are studied. The prevention liver cancer is explained. The treatment of each of the causes of liver cancer is analyzed.Публікація Adaptive human machine interaction approach for feature selection-extraction task in medical data mining(International Journal of Computing, 2018) Perova, I.; Bodyanskiy, Ye. V.Feature Selection task is one of the most complicated and actual in the areas of Data Mining and Human Machine Interaction. Many approaches to its solving are based on non-mathematical and presentative hypothesis. New approach to evaluation of medical features information quantity, based on optimized combination of feature selection and feature extraction methods is proposed. This approach allows us to produce optimal reduced number of features with linguistic interpreting of each of them. Hybrid system of feature selection/extraction based on Neural Network-Physician interaction is investigated. This system is numerically simple, can produce feature selection/extraction with any number of factors in online mode using neural network-physician interaction based on Oja’s neurons for online principal component analysis and calculating distance between first principal component and all input features. A series of experiments confirms efficiency of proposed approaches in Medical Data Mining area and allows physicians to have the most informative features without losing their linguistic interpreting.Публікація Advances in cryopreservation of alginate-encapsulated stem cells and analysis of cryopreservation outcome(Інститут проблем кріобіології та кріомедицини НАН України, 2018) Gryshkov, O.; Mutsenko, V.; Tymkovych, M.; Tarusin, D.; Sirotinskaya, V.; Braslavsky, I.; Аврунін, О. Г.; Glasmacher, B.Advances in cryopreservation of alginate-encapsulated stem cells and analysis of cryopreservation outcome is described.Публікація Aerodynamic Features of the Olfactory area in Nasal Breathing(RS Global S. z O.O., Warsaw, Poland, Science Review, 2017) Носова, Я. В.; Аврунін, О. Г.; Shushliapina, N. O.The passive of air through the upper nasal passage ensures the delivery of odorivector molecules to sensitive areas of the olfactory analyzer. The study of the characteristics of the air flow in the upper nasal passage allows us to determine the boundaries of the near-wall laminar air sublayer and to study nasal aerodynamics at the micro level. Turbulent flow contributes to the excessive drying of the mucous membrane of the nasal cavity, leading to its morphological rearrangement towards the subatrophic process. It was found out that the thickness of the laminar sublayer is about 1 mm, therefore, the lining of the mucous membrane is subjected to drying with an increase in the turbulence of the flow at the sites of narrowing of the nasal cavity (olfactory cleft).Публікація Aerodynamics Characteristics with Typical Nasal Breathing Disorders(Кременчуцький авіаційний коледж, 2018) Ibrahim Younouss Abdelhamid; Аврунін, О. Г.An enlarged nasopharyngeal tonsil, curvature of the nasal septum and chronic rhinosinusitis and other disorders causing difficulty in nasal breathing, but the violation of breathing through the nose can be in the usual runny nose, and when foreign bodies get into the nasal passages. Objective information about the physiological processes occurring in the nasal airways allows us to select a suitable treatment strategy based on functional information.Публікація An Attempt of Determining the Force Characteristics of Fields in Magnetic Stereotactic System(International Journal of Engineering Science and Innovative Technology (IJESIT), 2012) Аврунін, О. Г.; Elamir Abu Abaida Ali. Osman; Mustafa O. Ali; P. Chandra SekharMethod for analytical determination of the components of magnetic field induction vector and gradient characteristics of magnetic field in stereotactic magnetic neurosurgery systems has been investigated. Components of power vector acting on a surgical instrument from magnetic coil field have been determined and the analysis of topography of magnetic field power characteristics has been carried out.Публікація Analysis data for development of multifunctional computer-aided rhinomanometer(ХНУРЭ, 2011) Аврунін, О. Г.; Farouk, H.Dept. of BME, Alaflaj Community College of Alkharj University, Saudi Arabia A scheme of modern multifunctional rhinomanometer is proposed. The role of main parameters (airflow, pressure, respiratory resistance and power of nasal airway) and diagnostic criteria for functional diagnostics of upper respiratory airway diseases are described. Principles of design and components of multifunctional rhinomanometer are discussed. Diagnostic possibilities of the rhinomanometer for evidence-based medicine conception are described.