Progress and chellenges in electrochemiluminescent aptasensors

Muzyka, K.; Muhammad Saqib; Zhongyuan Liu; Wei Zhang; Guobao Xu

Публікація:
Progress and chellenges in electrochemiluminescent aptasensors

dc.contributor.author	Muzyka, K.
dc.contributor.author	Muhammad Saqib
dc.contributor.author	Zhongyuan Liu
dc.contributor.author	Wei Zhang
dc.contributor.author	Guobao Xu
dc.date.accessioned	2017-11-03T07:38:14Z
dc.date.available	2017-11-03T07:38:14Z
dc.date.issued	2017
dc.description.abstract	The importance of developing new diagnostic and detection technologies for the growing number of sensing challenges is rising each year. Here, we present a comprehensive and concise review on electrochemiluminescent (ECL) aptasensors by putting special emphasis on its characteristic features, advances, challenges, and applications of ECL based aptasensors. ECL is an ideal tool for constructing such sensors because of its inherent characteristics and can be easily integrated into aptamer based sensing platforms. This review summarizes the "synergistic benefits" of ECL aptamer-based sensors; classifications of ECL aptamer-based assay designs, and signal amplification strategies. This critical review highlights the effects of integration of nanomaterials, immobilization techniques, and amplification/detection strategies on the analytical performance of ECL based aptasensors. Moreover, several proof-of-concepts with appropriate figures and explanations have been shown to provide a general guide for the design of ECL aptasensors, and to stimulate further application of these ECL aptasensors. Finally, we conclude with the remaining challenges and opportunities to inspire further developments in ECL aptasensors.	uk_UA
dc.identifier.citation	: Kateryna Muzyka, Muhammad Saqib, Zhongyuan Liu, Wei Zhang and Guobao Xu, PROGRESS AND CHALLENGES IN ELECTROCHEMILUMINESCENT APTASENSORS, Biosensors and Bioelectronic, http://dx.doi.org/10.1016/j.bios.2017.01.015	uk_UA
dc.identifier.uri	http://openarchive.nure.ua/handle/document/4069
dc.language.iso	en	uk_UA
dc.publisher	PII: S0956-5663(17)30015-5 DOI: http://dx.doi.org/10.1016/j.bios.2017.01.015 Reference: BIOS9480	uk_UA
dc.subject	diagnostic and detection technologies, aptasensor, ECL	uk_UA
dc.title	Progress and chellenges in electrochemiluminescent aptasensors	uk_UA
dc.type	Book	uk_UA
dspace.entity.type	Publication