Перегляд за автором "Wei Zhang"

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  • Зображення мініатюри
    Публікація
    Artemisinin-luminol chemiluminescence for forensic bloodstain detection using smart phone as detector
    (Subscriber access provided by TRENT UNIV, 2017) Muzyka, K.; Chao Wang; Wenyue Gao; Shimeles Addisu Kitte; Jianping Li; Wei Zhang
    Forensic luminol chemiluminescence test is one of the most sensitive and popular methods for the determination oflatent bloodstains. It mainly uses hydrogen peroxide or sodium perborate as coreactants. The easy decomposition of hydrogen peroxide and sodium perborate in the presence of many ions significantly affects the selectivity. Artemisinin is a natural peroxide that is quite stable in the presence of common ions. In the present study, artemisinin has been exploited for the forensic bloodstain chemiluminescence detection for the first time. Using smart phone as cost-effective portable detector, the visual detection of bloodstains has been achieved with a dilution factor of blood upto 100000. Moreover, this system shows excellent selectivity against many common species. It can well differentiate bloodstains from other stains, such as coffee, brown sugar, and black tea. Both favourable sensitivity and selectivity makes the present method promising in forensic detection.
  • Зображення мініатюри
    Публікація
    Progress and chellenges in electrochemiluminescent aptasensors
    (PII: S0956-5663(17)30015-5 DOI: http://dx.doi.org/10.1016/j.bios.2017.01.015 Reference: BIOS9480, 2017) Muzyka, K.; Muhammad Saqib; Zhongyuan Liu; Wei Zhang; Guobao Xu
    The importance of developing new diagnostic and detection technologies for the growing number of sensing challenges is rising each year. Here, we present a comprehensive and concise review on electrochemiluminescent (ECL) aptasensors by putting special emphasis on its characteristic features, advances, challenges, and applications of ECL based aptasensors. ECL is an ideal tool for constructing such sensors because of its inherent characteristics and can be easily integrated into aptamer based sensing platforms. This review summarizes the "synergistic benefits" of ECL aptamer-based sensors; classifications of ECL aptamer-based assay designs, and signal amplification strategies. This critical review highlights the effects of integration of nanomaterials, immobilization techniques, and amplification/detection strategies on the analytical performance of ECL based aptasensors. Moreover, several proof-of-concepts with appropriate figures and explanations have been shown to provide a general guide for the design of ECL aptasensors, and to stimulate further application of these ECL aptasensors. Finally, we conclude with the remaining challenges and opportunities to inspire further developments in ECL aptasensors.