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\b\fs20\lang2057\langfe1049\langnp2057\insrsid13575053\charrsid2824699 , }{\rtlch\fcs1 \ab\af0\afs20 \ltrch\fcs0 \b\fs20\lang1033\langfe1049\langnp1033\insrsid13575053 T}{\rtlch\fcs1 \ab\af0\afs20 \ltrch\fcs0 
\b\fs20\lang2057\langfe1049\langnp2057\insrsid13575053\charrsid2824699  .}{\rtlch\fcs1 \ab\af0\afs20 \ltrch\fcs0 \b\fs20\lang1033\langfe1049\langnp1033\insrsid13575053 P}{\rtlch\fcs1 \ab\af0\afs20 \ltrch\fcs0 
\b\fs20\lang2057\langfe1049\langnp2057\insrsid13575053\charrsid2824699 . }{\rtlch\fcs1 \ab\af0\afs20 \ltrch\fcs0 \b\fs20\lang1033\langfe1049\langnp1033\insrsid13575053 Yarmak}{\rtlch\fcs1 \ab\af0\afs20 \ltrch\fcs0 
\b\fs20\up7\lang2057\langfe1049\langnp2057\insrsid13575053\charrsid2824699 1}{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\lang2057\langfe1049\langnp2057\insrsid16265896\charrsid2824699 
\par }\pard \ltrpar\ql \li0\ri0\sa120\nowidctlpar\wrapdefault\aspalpha\faauto\rin0\lin0\itap0 {\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\up6\lang1033\langfe1049\langnp1033\insrsid16265896 1}{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang1033\langfe1049\langnp1033\insrsid16265896  }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270 Department of biochemical, {\*\xmlopen\xmlns2{\factoidname PlaceType}}Institute{\*\xmlclose} of 
{\*\xmlopen\xmlns2{\factoidname PlaceName}}Dermatology{\*\xmlclose} and Venerology, Med. Sci. Acad. of {\*\xmlopen\xmlns2{\factoidname place}}{\*\xmlopen\xmlns2{\factoidname country-region}}Ukraine{\*\xmlclose}{\*\xmlclose}
. Chernyshevskiy Str. 7/9, Kharkov-61057, {\*\xmlopen\xmlns2{\factoidname place}}{\*\xmlopen\xmlns2{\factoidname country-region}}Ukraine{\*\xmlclose}{\*\xmlclose}. }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang1033\langfe1049\langnp1033\insrsid16265896 
\par }\pard \ltrpar\ql \li0\ri0\nowidctlpar\wrapdefault\aspalpha\faauto\rin0\lin0\itap0\pararsid15492270 {\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\up6\lang1033\langfe1049\langnp1033\insrsid16265896 2 }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270 Department}{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270\charrsid11821112  }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270 of}{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270\charrsid11821112  }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270 biophysics}{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270\charrsid11821112 , }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270 A.Ya. Usikov Institute}{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270\charrsid11821112  }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270 for}{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270\charrsid11821112  }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270 Radiophysics and Electronics}{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270\charrsid11821112 , }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270 Nat}{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270\charrsid11821112 . }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270 Acad. of Sci. of {\*\xmlopen\xmlns2{\factoidname place}}{\*\xmlopen\xmlns2{\factoidname country-region}}Ukraine{\*\xmlclose}{\*\xmlclose}.}{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270\charrsid13774181  }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang1033\langfe1049\langnp1033\insrsid15492270 {\*\xmlopen\xmlns2{\factoidname address}}{\*\xmlopen\xmlns2{\factoidname Street}}
Proskura St.{\*\xmlclose}{\*\xmlclose}, 12, Kharkov-61085, {\*\xmlopen\xmlns2{\factoidname place}}{\*\xmlopen\xmlns2{\factoidname country-region}}Ukraine{\*\xmlclose}{\*\xmlclose}. }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang2057\langfe1049\langnp2057\insrsid15492270\charrsid15492270 E-mail: }{\field\flddirty{\*\fldinst {\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang2057\langfe1049\langnp2057\insrsid15492270\charrsid15492270 
 HYPERLINK "mailto:dreval@ire.kharkov.ua" }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang1033\langfe1049\langnp1033\insrsid12523220\charrsid11820637 {\*\datafield 
00d0c9ea79f9bace118c8200aa004ba90b020000001700000016000000640072006500760061006c0040006900720065002e006b006800610072006b006f0076002e00750061000000e0c9ea79f9bace118c8200aa004ba90b3a0000006d00610069006c0074006f003a00640072006500760061006c004000690072006500
2e006b006800610072006b006f0076002e0075006100000000000000030000000000}}}{\fldrslt {\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \cs67\i\fs20\ul\cf2\lang2057\langfe1049\langnp2057\insrsid15492270\charrsid15492270 dreval@ire.kharkov.ua}}}\sectd 
\sbknone\linex0\headery708\footery708\sectdefaultcl\sftnbj {\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang2057\langfe1049\langnp2057\insrsid15492270\charrsid15492270   
\par }\pard \ltrpar\qc \li0\ri0\nowidctlpar\wrapdefault\aspalpha\faauto\rin0\lin0\itap0 {\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang1033\langfe1049\langnp1033\insrsid16265896 
\par }\pard \ltrpar\qj \fi360\li0\ri0\nowidctlpar\wrapdefault\aspalpha\faauto\rin0\lin0\itap0 {\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044 
One of the main purposes of advanced biotechnology is designing and application of medical drugs and also diagnostics methods of new generation in clinic.}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044  }{
\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044 
Modern medical and biologic researches have been shown that various pharmacological preparations, including local anesthetics, have a number of limitations in the using because of serious allergic reactions}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang1033\langfe1049\langnp1033\insrsid6113993 .}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044 
\par }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 Presently}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044 , }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang1033\langfe1049\langnp1033\insrsid6113993 the mechanism action}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang1033\langfe1049\langnp1033\insrsid3606044\charrsid3606044  of }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 local}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 anesthetics}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang1033\langfe1049\langnp1033\insrsid3606044\charrsid3606044 as articaine, ubistesin and septonest}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  which }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 are}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 tertiary}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 amines}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  and }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 that}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 under}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 physiologic}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 conditions}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 exist}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 in}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 a}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 mixture}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 of}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 protonated}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 and}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 neutral}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 forms are intensively investigated}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044 . }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid15492068 T}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 he charged forms appear to be 
more potent than the neutral forms once they gain access to the local anesthetic binding site on the cytoplasmic \'93side\'94 of the conducting pore of the Na channel [}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid3606044 1}{
\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 ]. }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid15492068 It is }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid9191950 assumed }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid15492068 that }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid15492068 a}{\rtlch\fcs1 
\af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 ctivation of transmembrane TRPV1 channel}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid733684 s}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044  assists permeation of compounds similar to tertiary amines}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid733684  (for example QX-314)}{\rtlch\fcs1 \af0\afs20 
\ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044  to the cytoplasmic compartment, where they potently}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid3606044  blocks Na channel }{\rtlch\fcs1 \af0\afs20 
\ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044\charrsid3606044 [}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3606044 2}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 ].}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang1033\langfe1049\langnp1033\insrsid7407958\charrsid7407958 
Red}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid7407958\charrsid7407958  blood }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang1033\langfe1049\langnp1033\insrsid7407958\charrsid7407958 cells}{\rtlch\fcs1 \af0\afs20 
\ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid7407958\charrsid7407958  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang1033\langfe1049\langnp1033\insrsid7407958\charrsid7407958 like lymphocytes are informative objects at development of human organisms
\rquote  sensitization. }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid7407958\charrsid7407958 It is know}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid9797176 n}{\rtlch\fcs1 \af0\afs20 
\ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid7407958\charrsid7407958  that hydration of transmembrane TRP channels represents their structurally-dynamic properties resulting in redistribution between quantity of the bound and free water.}{
\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid7407958  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3739595\charrsid3739595 
By means of EHF-dielectrometry method it is shown that stimulation of red blood cells by articaine, ubistesin and septonest has been differently reflected in change of a real part of permittivity (}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\insrsid3739595\charrsid3739595 {\field{\*\fldinst SYMBOL 101 \\f "Symbol" \\s 10}{\fldrslt\f3\fs20}}}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\insrsid3739595\charrsid3739595 {\field{\*\fldinst SYMBOL 162 \\f "Symbol" \\s 10}{\fldrslt\f3\fs20}}}{
\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid3739595\charrsid3739595 ).}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid13397298  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid10493515\charrsid10493515 Findings by method EHF-dielectrometry and also erythrocyte sedimentation rate were good correlated (}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang1033\langfe1049\langnp1033\insrsid10493515\charrsid10493515 r}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid10493515\charrsid10493515  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid7086534 {\field{\*\fldinst SYMBOL 179 \\f "Symbol" \\s 10}{\fldrslt\f3\fs20}}}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid10493515\charrsid10493515  0,}{\rtlch\fcs1 
\af0\afs20 \ltrch\fcs0 \fs20\lang1033\langfe1049\langnp1033\insrsid7086534\charrsid7086534 92}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid10493515\charrsid10493515 
) that allows to recommend this radio physical method for diagnostics of early revealing of a sensitization to medicinal allergens.}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid3606044 
\par {\listtext\pard\plain\ltrpar \rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang9\langfe1049\langnp9\insrsid15213992\charrsid15213992 \hich\af0\dbch\af0\loch\f0 1.\tab}}\pard \ltrpar\ql \li360\ri0\nowidctlpar
\tx360\wrapdefault\aspalpha\faauto\ls1\ilvl3\rin0\lin360\itap0\pararsid11888958 {\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang9\langfe1049\langnp9\insrsid15213992\charrsid15213992 Butterworth }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid15213992 J}{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang9\langfe1049\langnp9\insrsid15213992\charrsid15213992 ., }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid15213992 Gerry S.}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044  Local anesthetics: a new hydrophylic pathway for the drug-receptor reaction}{
\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang1033\langfe1049\langnp1033\insrsid3606044\charrsid3606044 // }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 Anesthesiology.}{\rtlch\fcs1 \af0\afs20 
\ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid15213992 -}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid12734537 2}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 009}{
\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid15213992 .-}{\rtlch\fcs1 \ab\af0\afs20 \ltrch\fcs0 \b\fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid15213992 111}{\rtlch\fcs1 \ab\af0\afs20 \ltrch\fcs0 
\b\fs20\lang9\langfe1049\langnp9\insrsid12734537 , }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid12734537\charrsid12734537 N 1}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid15213992 .-}{\rtlch\fcs1 
\af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid12734537 P. }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid3606044\charrsid3606044 12-14}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid12734537 .}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid3606044 
\par {\listtext\pard\plain\ltrpar \rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid12734537 \hich\af0\dbch\af0\loch\f0 2.\tab}}\pard \ltrpar\ql \fi66\li360\ri0\nowidctlpar
\tx360\wrapdefault\aspalpha\faauto\ls1\ilvl3\rin0\lin360\itap0\pararsid5245883 {\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid12734537 Binshtok}{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid12734537  }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid12734537 A.M}{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid12734537 , }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid12734537 Bean}{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid12734537  }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid12734537 B.P}{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid12734537 , }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid12734537 Woolf}{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 
\i\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid12734537  }{\rtlch\fcs1 \ai\af0\afs20 \ltrch\fcs0 \i\fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid12734537 C.J.}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 Inhibition}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 of}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 nociceptors}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 by}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 TRPV}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid3606044 -1-}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 mediated}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 entry}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 of}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 impermeant}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 sodium}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 channel}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 blockers}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid11888958  //}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang2057\langfe1049\langnp2057\insrsid11888958\charrsid3606044  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 Nature}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958 .-}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 
2007}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958 .-}{\rtlch\fcs1 \ab\af0\afs20 \ltrch\fcs0 \b\fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid12734537 449}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang9\langfe1049\langnp9\insrsid11888958 .-P. }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 607\endash }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958 6}{
\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958\charrsid3606044 10}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid11888958 .}{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\lang1033\langfe1049\langnp1033\insrsid3107059  }{\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\lang9\langfe1049\langnp9\insrsid3107059\charrsid10493515 
\par }}